National Immunization Schedule (NIS) of India – Complete 2024 Guide for Nurses
Updated and simplified National Immunization Schedule (NIS) for India – based on Ministry of Health & Family Welfare (MoHFW) and National Health Mission (NHM) guidelines for pregnant women, infants and children. Designed for nursing and medical competitive exams by GKQuizNursing.
Table of Contents
- Goals of National Immunization Schedule
- Schedule for Pregnant Women (Td)
- Schedule for Infants (Birth to 1 year)
- Schedule for Children (16 months to 16 years)
- Important Notes, Memory Tricks & Nursing Tips
- MCQs for Nursing Exams (with Answers)
- Frequently Asked Questions
1. Goals of National Immunization Schedule
- Provide free and universal vaccination to all eligible beneficiaries under UIP.
- Prevent childhood mortality and morbidity due to vaccine preventable diseases.
- Ensure at least 90% full immunization coverage in all districts (Mission Indradhanush target).
- Protect pregnant women and newborns from tetanus and other infections.
2. National Immunization Schedule for Pregnant Women (India)
| Vaccine | When to Give | Dose | Route | Site |
|---|---|---|---|---|
| Td-1 (Tetanus & adult diphtheria) | Early in pregnancy (as soon as pregnancy is detected) | 0.5 ml | Intramuscular | Upper arm |
| Td-2 | 4 weeks after Td-1 | 0.5 ml | Intramuscular | Upper arm |
| Td Booster | If woman has received 2 TT/Td doses in a pregnancy within the last 3 years – only 1 booster dose is needed | 0.5 ml | Intramuscular | Upper arm |
3. National Immunization Schedule for Infants (Birth–12 months)
At Birth
| Vaccine | When to Give | Dose | Route | Site |
|---|---|---|---|---|
| BCG | At birth or as early as possible up to 1 year | 0.1 ml (0.05 ml up to 1 month age) | Intradermal | Left upper arm |
| Hepatitis-B Birth Dose | At birth or within 24 hours | 0.5 ml | Intramuscular | Antero-lateral side of mid-thigh (left) |
| OPV-0 (Oral Polio Vaccine) | At birth or within first 15 days | 2 drops | Oral | Oral |
At 6, 10 and 14 Weeks
| Age | Vaccines | Remarks |
|---|---|---|
| 6 weeks | OPV-1, Pentavalent-1 (DPT+HepB+Hib), Rotavirus-1, fractional IPV-1 (fIPV-1), PCV-1* | PCV in selected states/districts; rotavirus & PCV where introduced |
| 10 weeks | OPV-2, Pentavalent-2, Rotavirus-2 | Catch up allowed till 1 year |
| 14 weeks | OPV-3, Pentavalent-3, Rotavirus-3, fractional IPV-2 (fIPV-2), PCV-2* | fIPV given intradermally in right upper arm |
At 9–12 Months
| Vaccine | When to Give | Dose | Route | Site |
|---|---|---|---|---|
| MR-1 (Measles–Rubella 1st dose) | 9 completed months–12 months (can be given up to 5 years if missed) | 0.5 ml | Subcutaneous | Right upper arm |
| JE-1** (where JE programme exists) | 9–12 months | 0.5 ml | SC or IM (as per vaccine type) | Left upper arm or antero-lateral thigh |
| PCV Booster* | 9–12 months (after primary 6 & 14 week doses) | 0.5 ml | Intramuscular | Antero-lateral thigh |
| Vitamin A 1st dose | At 9 months with MR-1 | 1 ml (1 lakh IU) | Oral | Oral |
4. National Immunization Schedule for Children (16 months–16 years)
| Age | Vaccine | Dose | Route | Site |
|---|---|---|---|---|
| 16–24 months | DPT Booster-1 | 0.5 ml | Intramuscular | Antero-lateral thigh |
| MR-2 | 0.5 ml | Subcutaneous | Right upper arm | |
| OPV Booster | 2 drops | Oral | Oral | |
| JE-2** (where applicable) | 0.5 ml | SC or IM | Left upper arm / thigh | |
| Vitamin A 2nd–9th doses | 2 ml (2 lakh IU) each dose | Oral | Oral | |
| 5–6 years | DPT Booster-2 | 0.5 ml | Intramuscular | Upper arm |
| 10 years | Td | 0.5 ml | Intramuscular | Upper arm |
| 16 years | Td | 0.5 ml | Intramuscular | Upper arm |
5. Important Notes, Memory Tricks & Nursing Tips
- Site rule:
- BCG – intradermal, left upper arm
- MR – subcutaneous, right upper arm
- Hep-B & Pentavalent – IM, antero-lateral thigh
- fIPV – intradermal, right upper arm
- “6–10–14” weeks formula: OPV, Pentavalent, Rotavirus (and PCV/fIPV where applicable).
- “9 months combo”: MR-1 + JE-1 (in endemic districts) + PCV booster + Vitamin A 1st dose.
- Vitamin A doses: 1st at 9 months (1 lakh IU), then 2nd–9th every 6 months till 5 years (2 lakh IU each).
- Pregnant woman already fully immunized in last 3 years: give only one Td booster.
- Open vial policy, cold chain, and AEFI (Adverse Event Following Immunization) should always be part of nursing counselling.
6. MCQs on National Immunization Schedule (for NORCET / Staff Nurse / CHO)
1. BCG vaccine under NIS is given at which site?
A. Right deltoid
B. Left upper arm intradermal
C. Right thigh IM
D. Left gluteal
Answer: B.
Nursing point: BCG always left upper arm intra-dermal – easy to remember: “B for BCG, L for Left.”
2. Which combination of vaccines is given at 6 weeks under NIS?
A. BCG + MR
B. OPV-1 + Pentavalent-1 + Rotavirus-1 + fIPV-1 (+ PCV-1 where applicable)
C. OPV-2 + MR-1
D. DPT-Booster + OPV-Booster
Answer: B.
3. Td vaccine for pregnant women is preferred because:
A. It covers only tetanus
B. It covers tetanus and adult diphtheria
C. It is oral vaccine
D. It is cheaper but less effective
Answer: B.
4. Vitamin A 2nd–9th doses are given:
A. Every month till 5 years
B. Every 3 months till 3 years
C. Every 6 months from 16–18 months to 5 years
D. Only at 9 months and 18 months
Answer: C.
5. OPV-0 should ideally be given:
A. Within first 15 days of life
B. At 6 weeks
C. At 10 weeks
D. At 9 months
Answer: A.
6. Under NIS, MR-1 is scheduled at:
A. At birth
B. 6 weeks
C. 9–12 months
D. 5–6 years
Answer: C.
7. Which of the following vaccines is given intradermally?
A. BCG and fIPV
B. Pentavalent and Hep-B
C. OPV and Rotavirus
D. MR and JE
Answer: A.
8. DPT Booster-2 under NIS is given at:
A. 16–24 months
B. 9–12 months
C. 5–6 years
D. 10 years
Answer: C.
9. For a 10-year-old child, which vaccine is recommended in NIS?
A. BCG
B. MR-1
C. Td
D. PCV Booster
Answer: C.
10. JE vaccine in NIS is:
A. Given to all children in India
B. Given only in selected endemic districts
C. Given only to adults
D. Not part of UIP
Answer: B.
7. Frequently Asked Questions (NIS for India)
Q1. What is the difference between UIP and NIS?
Answer: Universal Immunization Programme (UIP) is the national programme under MoHFW that provides vaccines. The National Immunization Schedule (NIS) is the list of vaccines with exact ages, doses, route and site recommended under UIP.
Q2. Is TT still used for pregnant women?
Answer: Current guidelines recommend Td (tetanus + adult diphtheria) instead of plain TT to give additional protection from diphtheria.
Q3. Are PCV and JE given to all children?
Answer: PCV and JE are given in selected states and endemic districts as per Government of India instructions. Always check your state immunization guidelines.
Q4. Can multiple vaccines be given in one visit?
Answer: Yes. For example, at 9 months a child can receive MR-1, PCV booster, JE-1 and Vitamin A together at different sites using separate syringes.
Q5. Which document should the nurse always carry for reference?
Answer: The latest National Immunization Schedule chart and Immunization Handbook for Medical Officers / ANMs issued by MoHFW & NHM.